Takeo had short, spiky black hair similar to his older brother Tanjiro and his father. Like the rest of his siblings, Takeo had a light pale complexion which contrasted with his dark red eyes, which also had white pupils. He was significantly similar in appearance to Tanjiro, except he had a mole beneath his right eye and lacked the scar on the top of his forehead.
Takeo wore a gray kimono top and green kimono jacket, along with a pair of baggy pants and boots. He also sported a turquoise and black patterned scarf.
Takeo cared about his family very much, showing visible dismay at the prospect of Tanjiro suddenly leaving for the town.
Takeo grew up on a mountain alongside his siblings and mother. He is the second oldest son of the Kamado family.
While Tanjiro is in the town, Takeo and the rest of his family aside from Nezuko Kamado are attacked and killed by Muzan.
After Tanjiro gets knocked unconscious by Giyu Tomioka, Takeo and his deceased siblings and mother are seen looking over Tanjiro with worried expressions.
When Tanjiro fights against Daki, Takeo is briefly seen in Tanjiro's memory, where he tells him that he and Nezuko are similar in that they lack concern for themselves despite showing much concern for others. Takeo also states his worry for Nezuko possibly losing something precious to her as a result of this trait.