Sometime in the past, the Fuji family was saved from Demons by the Demon Slayer Corps. To express their gratitude, the family designed their family crest with a Wisteria flower so corps members would be able to identify the home, and stay there free of charge.
- During the Final Selection, Wisteria is used to keep the Demons trapped on Fujikasane Mountain.
- Following the Final Selection, Wisteria is used to engrave the ranks of the corps members on the back of their hands.
- Wisteria can be used to create poisons which can paralyze regular Demons and immobilize Lower Ranks of the Twelve Kizuki. In high enough concentrations, as used by Shinobu Kocho, these poisons are shown to be capable of dissolving almost any demon, negating their regeneration powers.
- Wisteria is used by Shinobu to create a medication which would turn a Demon back into a human.